What is Belbuca?


Belbuca (buprenorphine) is a medication used to treat chronic pain in patients requiring a long-term opioid analgesic. It is a partial opioid agonist, which means it binds to the same receptors as other opioids but has a lower potential for abuse and dependence. Belbuca is available as a buccal film that is applied to the inner cheek for absorption.

Historical context

Belbuca was approved by the FDA in 2015 as a new formulation of buprenorphine specifically for the treatment of chronic pain. It was developed to provide an alternative to traditional opioid medications and reduce the risk of abuse and addiction.

Medical formulation

Belbuca is available as a buccal film in various strengths, ranging from 75 mcg to 900 mcg. The film is applied to the inner cheek, where it adheres and dissolves, allowing the medication to be absorbed directly into the bloodstream.

How long does Belbuca stay in your system?

The half-life of buprenorphine, the active ingredient in Belbuca, is approximately 24 to 42 hours. It takes about 5 to 8 days for the drug to be eliminated from the body after the last dose.


Belbuca buccal film is a rectangular, yellowish, translucent film with a "B" and the strength imprinted on it. The film is available in different dosages, with the specific strength indicated on the packaging.

Common films

Belbuca is available in the following strengths as buccal films: 75 mcg, 150 mcg, 300 mcg, 450 mcg, 600 mcg, 750 mcg, and 900 mcg.

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