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What is Speedball?
Speedball is a slang term for a dangerous combination of drugs, typically involving an opioid (such as heroin/fentanyl) and the stimulant cocaine. This combination is highly risky, as the simultaneous use of an opioid and a stimulant can lead to significant cardiovascular and respiratory complications, often resulting in overdose and death.
The origin of the nickname Speedball is thought to come from the contrasting effects of the drugs involved: the "speed" from the stimulant and the "ball" or "downer" effect from the opioid. This street name has been in use for several decades and is widely recognized.