What is oxymorphone?


Oxymorphone is a semi-synthetic opioid derived from thebaine and is used to treat moderate to severe pain. It is more potent than morphine but has a shorter duration of action.

Historical context

Oxymorphone was first synthesized in the early 20th century and gained FDA approval in the United States in 1959. It has been used for pain management in medical settings since then.

Medical formulations

Oxymorphone is available in immediate-release and extended-release oral tablets (e.g., Opana®️, Opana ER®️) and injectable forms.

How long does oxymorphone stay in your system?

Oxymorphone has a half-life of around 9 to 11 hours. It takes roughly 45 to 55 hours for the drug to be completely eliminated from the body.

Street names

O Bomb, Stop Signs, Mrs. O, Blue Heaven


Oxymorphone pills are typically round or oblong and come in various colors, such as white, green, or blue, depending on the formulation and dosage. They may be imprinted with the dosage and the manufacturer's logo.

Common pills

  • Round, white pill with "54 814" imprinted on one side (5 mg tablet)
  • Round, green pill with "54 915" imprinted on one side (15 mg extended-release tablet)
  • Round, blue pill with "54 199" imprinted on one side (30 mg extended-release tablet)

Warning: Consuming illicit drugs, including pressed pills, may result in unintended fentanyl exposure, leading to potentially fatal consequences. Exercise caution and consider using fentanyl testing strips to identify the presence of this dangerous substance in street drugs.

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