Drugs

7-OH: Quick Questions, Straight Answers

Quick answers about 7-OH: how it’s different from kratom, whether it’s addictive, what withdrawal is like, and if medication can help.

By:
Arthur Robin Williams, MD
7-OH is a potent opioid-like substance often sold as kratom. Learn what it is, why it’s risky, and what to do if you want to stop.
Icon of shield with check mark inside
Medically reviewed by
Last updated on Feb 05, 2026

Is 7-OH the same as kratom?

No. While 7-OH comes from the kratom plant (typically present in only trace amounts), many 7-OH products contain concentrated or synthetic (lab made) forms. 7-OH is much stronger than mitragynine (the main natural chemical in kratom) in how it acts on the brain’s opioid receptors. In practical terms, it behaves more like a prescription opioid than like “kratom.” It’s often safest to think of 7-OH as a different drug, not just another kratom product, because the potency and overdose risk can be much higher.

Is 7-OH addictive?  

Yes, highly. 7-OH binds strongly to opioid receptors and can lead to psychological and physical dependence, with withdrawal symptoms, much like prescription opioids.

How long does 7-OH withdrawal last? 

Withdrawal appears rapidly, often in less than a day since the last use, peaks in 2-3 days, and resolves in about a week, though sleep and mood problems can last longer. 

Is it safe to quit 7-OH suddenly?

Similarly to opioid painkillers, withdrawal is usually not dangerous, but it can be extremely uncomfortable, and even risky in people with underlying medical problems. Medication support can make stopping safer and more manageable.

Can medication help with 7-OH dependence?

Yes. A licensed clinician can help create a plan with medication, that can reduce withdrawal and cravings and make it easier and safer to stop.

Sources

Treatment that works is right at your fingertips.

Get started
X